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Recombinant STING/TMEM173 抗体 (AA 190-290)

The 兔 单克隆 anti-STING/TMEM173 antibody is suitable to detect STING/TMEM173 in samples from 人. It has been validated for IHC (p).
产品编号 ABIN7871634
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for Recombinant STING/TMEM173 抗体 (AA 190-290) (ABIN7871634)

抗原

See all STING/TMEM173 (TMEM173) 抗体
STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))

抗体类型

Recombinant Antibody

适用

  • 100
  • 33
  • 22
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1

宿主

  • 112
  • 10

克隆类型

  • 72
  • 50
单克隆

标记

  • 60
  • 8
  • 8
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This STING/TMEM173 antibody is un-conjugated

应用范围

  • 81
  • 33
  • 29
  • 29
  • 21
  • 19
  • 18
  • 13
  • 13
  • 13
  • 3
  • 3
  • 1
  • 1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

STING1-8187R
  • 抗原表位

    • 19
    • 15
    • 13
    • 9
    • 8
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 190-290

    原理

    ERIS Antibody / Endoplasmic reticulum interferon stimulator / STING1 (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    A recombinant partial protein sequence (within amino acids 190-290) from the human protein was used as the immunogen for the ERIS antibody.

    亚型

    IgG, kappa
  • 应用备注

    Optimal dilution of the STING1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the STING1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))

    别名

    ERIS

    背景

    TMEM173 (transmembrane protein 173), also called STING1 and ERIS (Endoplasmic reticulum interferon) is a 379 amino acid protein encoded by a gene mapping to human chromosome 5. With 181 million base pairs encoding around 1,000 genes, chromosome 5 is about 6 % of human genomic DNA. It is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.

    UniProt

    Q86WV6

    途径

    Activation of Innate immune Response
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