Recombinant STING/TMEM173 抗体 (AA 190-290)
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北京 101111
Quick Overview for Recombinant STING/TMEM173 抗体 (AA 190-290) (ABIN7871634)
抗原
See all STING/TMEM173 (TMEM173) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- AA 190-290
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原理
- ERIS Antibody / Endoplasmic reticulum interferon stimulator / STING1 (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- A recombinant partial protein sequence (within amino acids 190-290) from the human protein was used as the immunogen for the ERIS antibody.
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亚型
- IgG, kappa
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应用备注
- Optimal dilution of the STING1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the STING1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))
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别名
- ERIS
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背景
- TMEM173 (transmembrane protein 173), also called STING1 and ERIS (Endoplasmic reticulum interferon) is a 379 amino acid protein encoded by a gene mapping to human chromosome 5. With 181 million base pairs encoding around 1,000 genes, chromosome 5 is about 6 % of human genomic DNA. It is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
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UniProt
- Q86WV6
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途径
- Activation of Innate immune Response
抗原
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