MFAP3 抗体 (AA 19-349)
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Quick Overview for MFAP3 抗体 (AA 19-349) (ABIN7871588)
抗原
See all MFAP3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 19-349
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原理
- MFAP3 Antibody / Microfibril-associated glycoprotein 3
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纯化方法
- Antigen affinity purified
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免疫原
- An E.coli-derived human recombinant protein (A19-N349) was used as the immunogen for the MFAP3 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the MFAP3 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the MFAP3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- MFAP3 (Microfibrillar Associated Protein 3 (MFAP3))
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别名
- MFAP3
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背景
- Microfibril-associated glycoprotein 3 (MFAP3), is a member of the MFAP family which play a role in microfibril assembly, elastinogenesis, and tissue homeostasis. The family members were identified as potential components of fibrillin-containing microfibrils, but they do not share structural similarities. MFAP3 is found in ocular zonules. Human MFAP3 is a serine-rich acidic protein located in zonular fibers and consists of an extracellular domain (ECD) containing one Ig-like C2-type domain, a single transmembrane domain, and a cytoplasmic domain. Within the ECD, mature human MFAP3 shares 74 % amino acid sequence identity with mouse and rat MFAP3. Among MFAP3-related pathways are degradation of the extracellular matrix and elastic fiber formation. MFAP is a candidate gene for heritable diseases affecting microfibrils.
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UniProt
- P55082
抗原
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