FSHB 抗体 (AA 19-130)
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Quick Overview for FSHB 抗体 (AA 19-130) (ABIN7871556)
抗原
See all FSHB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 19-130
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原理
- Zebrafish Fshb Antibody / Follicle stimulating hormone beta
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纯化方法
- Antigen affinity chromatography
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免疫原
- E. coli-derived zebrafish Fshb recombinant protein (amino acids E19-H130) was used as the immunogen for the Zebrafish Fshb antibody.
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亚型
- Ig Fraction
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anti-Follicle Stimulating Hormone, beta Polypeptide (FSHB) (AA 61-98) antibody
FSHB 适用: 人, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Follicle Stimulating Hormone, beta Polypeptide (FSHB) (AA 21-129) antibodyFSHB 适用: Pig WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Follicle Stimulating Hormone, beta Polypeptide (FSHB) (AA 19-129) antibodyFSHB 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 3C1E4 unconjugated
anti-Follicle Stimulating Hormone, beta Polypeptide (FSHB) (AA 21-130) antibodyFSHB 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Follicle Stimulating Hormone, beta Polypeptide (FSHB) antibodyFSHB 适用: 人 IHC 宿主: 小鼠 Monoclonal FSHb-1062 unconjugated
anti-Follicle Stimulating Hormone, beta Polypeptide (FSHB) (AA 36-64) antibodyFSHB 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB32962 unconjugated
anti-Follicle Stimulating Hormone, beta Polypeptide (FSHB) (AA 19-129) antibodyFSHB 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Follicle Stimulating Hormone, beta Polypeptide (FSHB) antibodyFSHB 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Follicle Stimulating Hormone, beta Polypeptide (FSHB) (AA 21-130) antibodyFSHB 适用: 小鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C2 unconjugated
anti-Follicle Stimulating Hormone, beta Polypeptide (FSHB) (AA 19-129) antibodyFSHB 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the Zebrafish Fshb antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Zebrafish Fshb antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- FSHB (Follicle Stimulating Hormone, beta Polypeptide (FSHB))
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别名
- Fshb
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背景
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Follicle-stimulating hormone (FSH) is a key glycoprotein hormone involved in the regulation of reproductive processes across vertebrate species. It is composed of a common alpha subunit and a hormone-specific beta subunit, with the beta subunit (Fshb) conferring biological specificity. In zebrafish (Danio rerio), the fshb gene encodes the beta subunit of FSH and is expressed in gonadotrope cells of the anterior pituitary.
Zebrafish Fshb plays a crucial role in the development and maturation of gametes, particularly in promoting folliculogenesis in females and spermatogonial proliferation in males. Its expression and secretion are primarily regulated by gonadotropin-releasing hormone (GnRH) and modulated by feedback from sex steroids and other endocrine factors within the hypothalamic-pituitary-gonadal (HPG) axis.
During zebrafish development, fshb expression becomes evident post-embryonically and increases with sexual maturation. Functional studies have shown that Fshb is essential for early-stage follicle development and the onset of puberty, while also contributing to basal steroidogenesis in the gonads.
Given the genetic accessibility and transparency of zebrafish, the fshb gene and its protein product are commonly used in reproductive biology, toxicology, and endocrine disruption studies. Zebrafish Fshb shares structural and functional homology with its mammalian counterparts, making it a valuable model for exploring conserved mechanisms of vertebrate reproduction.
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UniProt
- Q6TCF7
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途径
- Peptide Hormone Metabolism, Hormone Activity, C21-Steroid Hormone Metabolic Process
抗原
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