ITGA6 抗体 (AA 189-917)
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Quick Overview for ITGA6 抗体 (AA 189-917) (ABIN7871539)
抗原
See all ITGA6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 189-917
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原理
- Integrin alpha 6 Antibody / ITGA6
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纯化方法
- Affinity purified
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免疫原
- Amino acids Q189-K917 from the human protein were used as the immunogen for the Integrin alpha 6 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Integrin alpha 6 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- Store the Integrin alpha 6 antibody at -20oC.
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- ITGA6 (Integrin, alpha 6 (ITGA6))
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别名
- Integrin alpha 6
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背景
- Integrin alpha-6, also called VLA-6 or ITGA6B is a protein that in humans is encoded by the ITGA6 gene. This gene is mapped to 2q31.1. The ITGA6 protein product is the integrin alpha chain alpha 6. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Integrin alpha-6/beta-1 is a receptor for laminin on platelets. Integrin alpha-6/beta-4 is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome.
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UniProt
- P23229
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途径
- CXCR4-mediated Signaling Events, Brown Fat Cell Differentiation, Integrin Complex
抗原
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