SRCIN1 抗体 (AA 189-287)
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Quick Overview for SRCIN1 抗体 (AA 189-287) (ABIN7871525)
抗原
See all SRCIN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 189-287
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原理
- SRCIN1 Antibody
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纯化方法
- Antigen affinity purified
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免疫原
- Amino acids E189-E287 from the human protein were used as the immunogen for the SRCIN1 antibody.
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亚型
- IgG
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anti-SRC Kinase Signaling Inhibitor 1 (SRCIN1) (Internal Region) antibody
SRCIN1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-SRC Kinase Signaling Inhibitor 1 (SRCIN1) (Internal Region) antibodySRCIN1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-SRC Kinase Signaling Inhibitor 1 (SRCIN1) (Internal Region) antibodySRCIN1 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-SRC Kinase Signaling Inhibitor 1 (SRCIN1) (AA 189-287) antibodySRCIN1 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IHC, FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-SRC Kinase Signaling Inhibitor 1 (SRCIN1) (Center) antibodySRCIN1 适用: 人, 小鼠, 大鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the SRCIN1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the SRCIN1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- SRCIN1 (SRC Kinase Signaling Inhibitor 1 (SRCIN1))
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别名
- SRCIN1
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背景
- Using yeast 2-hybrid analysis, protein pull-down assays, and mutation analysis, it is showed that the first coiled-coil domain of rat Snip interacted with the N-terminal t-SNARE domain of Snap25 (600322). Biochemical studies demonstrated that Snip was tightly associated with rat brain cytoskeleton. Indirect immunofluorescence and confocal microscopy of rat PC12 pheochromocytoma cells revealed colocalization of Snip with Snap25 in the actin cytoskeleton, particularly in filopodia, lamellipodia, and neuritic extensions, including the tips. Overexpression of Snip or its Snap25-interacting domain inhibited calcium-dependent exocytosis from PC12 cells. It is concluded that SNIP is involved in regulation of neurosecretion, perhaps via its interaction with SNAP25 and the cytoskeleton.
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UniProt
- Q9C0H9
抗原
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