ALOX12 抗体 (AA 186-628)
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Quick Overview for ALOX12 抗体 (AA 186-628) (ABIN7871510)
抗原
See all ALOX12 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 186-628
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原理
- ALOX12 Antibody / 12S-lipoxygenase
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纯化方法
- Antigen affinity chromatography
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免疫原
- An E.coli-derived human recombinant protein (amino acids A186-R628) was used as the immunogen for the ALOX12 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the ALOX12 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the ALOX12 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- ALOX12 (Arachidonate 12-Lipoxygenase (ALOX12))
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别名
- ALOX12
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背景
- ALOX12, Arachidonate 12-lipoxygenase, is an enzyme that in humans is encoded by the ALOX12 gene. By fluorescence in situ hybridization, the ALOX12 gene is located in band 17p13.1. The gene consists of 14 exons with 13 introns and spans approximately 15 kb of DNA Arachidonate 12-lipoxygenase introduces a molecular oxygen into the C-12 position of arachidonic acid to produce 12(S)-hydroperoxy-5,8,10,14-eicosatetraenoic acid. The major pathway of arachidonic acid metabolism in human platelets proceeds via a 12-lipoxygenase enzyme. Expression of the LOG12 gene was detected in human erythroleukemia cells, platelets, and human umbilical vein endothelial cells by reverse transcription-PCR analysis.
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UniProt
- P18054
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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