NPM1 抗体 (AA 185-287)
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Quick Overview for NPM1 抗体 (AA 185-287) (ABIN7871493)
抗原
See all NPM1 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- AA 185-287
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原理
- NPM Antibody / Nucleophosmin (azide and preservative free)
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纯化方法
- Protein G affinity chromatography
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免疫原
- A portion of amino acids 185-287 from the human protein was used as the immunogen for the NPM antibody.
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亚型
- IgG1, kappa
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应用备注
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Optimal dilution of the NPM antibody should be determined by the researcher.
1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the NPM antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- NPM1 (Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1))
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别名
- NPM
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背景
- The protein encoded by the NPM1 gene is involved in several cellular processes, including centrosome duplication, protein chaperoning, and cell proliferation. The encoded phosphoprotein shuttles between the nucleolus, nucleus, and cytoplasm, chaperoning ribosomal proteins and core histones from the nucleus to the cytoplasm. This protein is also known to sequester the tumor suppressor ARF in the nucleolus, protecting it from degradation until it is needed. Mutations in this gene are associated with acute myeloid leukemia. [RefSeq]
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UniProt
- P06748
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途径
- Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
抗原
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