FOLR2 抗体 (AA 18-46)
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Quick Overview for FOLR2 抗体 (AA 18-46) (ABIN7871424)
抗原
See all FOLR2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 18-46
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原理
- FOLR2 Antibody / Folate Receptor beta
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 18-46 from the human protein were used as the immunogen for the FOLR2 antibody.
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亚型
- Ig Fraction
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应用备注
- The stated application concentrations are suggested starting points. Titration of the FOLR2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the FOLR2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))
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别名
- FOLR2
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背景
- FOLR2 is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68 % and 79 % sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients.
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UniProt
- P14207
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途径
- Dicarboxylic Acid Transport
抗原
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