TUBA1A 抗体 (AA 18-403)
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北京 101111
Quick Overview for TUBA1A 抗体 (AA 18-403) (ABIN7871414)
抗原
See all TUBA1A (Tuba1a) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 18-403
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原理
- TUBA1A Antibody / Tubulin Alpha
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纯化方法
- Affinity purified
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免疫原
- Recombinant human protein (amino acids N18-A403) was used as the immunogen for the TUBA1A antibody.
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亚型
- IgG
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anti-Tubulin, alpha 1a (Tuba1a) antibody
Tuba1a 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Tubulin, alpha 1a (Tuba1a) antibodyTuba1a 适用: 人 WB, ELISA, IHC, IF, IP, FACS 宿主: 小鼠 Monoclonal 7E5C12 unconjugated
anti-Tubulin, alpha 1a (Tuba1a) (AA 352-451) antibodyTuba1a 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2D2 unconjugated
anti-Tubulin, alpha 1a (Tuba1a) (C-Term) antibodyTuba1a 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tubulin, alpha 1a (Tuba1a) (C-Term) antibodyTuba1a 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tubulin, alpha 1a (Tuba1a) (acLys352) antibodyTuba1a 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Tubulin, alpha 1a (Tuba1a) (acLys40) antibodyTuba1a 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Tubulin, alpha 1a (Tuba1a) antibodyTuba1a 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal unconjugated
anti-Tubulin, alpha 1a (Tuba1a) (AA 30-229) antibodyTuba1a 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tubulin, alpha 1a (Tuba1a) (pTyr272) antibodyTuba1a 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the TUBA1A antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the TUBA1A antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- TUBA1A (Tuba1a) (Tubulin, alpha 1a (Tuba1a))
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别名
- TUBA1A
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背景
- Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. This gene encodes alpha tubulin and is highly similar to the mouse and rat Tuba1 genes. Northern blot studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q. Mutations in this gene cause lissencephaly type 3 (LIS3) - a neurological condition characterized by microcephaly, intellectual disability, and early-onset epilepsy caused by defective neuronal migration. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
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UniProt
- Q71U36
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途径
- Microtubule Dynamics, M Phase
抗原
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