Reelin 抗体 (AA 1796-2115)
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Quick Overview for Reelin 抗体 (AA 1796-2115) (ABIN7871363)
抗原
See all Reelin (RELN) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1796-2115
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原理
- Reelin Antibody / RELN
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纯化方法
- Protein A/G affinity
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免疫原
- A portion of amino acids 1796-2115 was used as the immunogen for the Reelin antibody.
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亚型
- IgG2b
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应用备注
- Optimal dilution of the Reelin antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Reelin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Reelin (RELN)
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别名
- Reelin
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背景
- Reelin (or Reln) is a large glycoprotein that is secreted by Cajal-Retzius cells in the forebrain and by granule neurons in the cerebellum. Reelin was shown to be mutated in reeler mice, a mutation that is associated with widespread disruption of laminated regions of the brain, leading to impaired motor coordination, tremors and ataxia. Reelin protein expression is complex and changes throughout development. Reelin appears to function upstream of Dab1, in a signaling pathway that controls cell positioning in the developing brain, and is also thought to be a direct effector of the neurotrophin BDNF.
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UniProt
- P78509
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途径
- Synaptic Membrane
抗原
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