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Reelin 抗体 (AA 1796-2115)

The 小鼠 单克隆 anti-Reelin antibody (Clone RELN-4498) (ABIN7871362) specifically detects Reelin in IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7871362
发货至: 中国
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Quick Overview for Reelin 抗体 (AA 1796-2115) (ABIN7871362)

抗原

See all Reelin (RELN) 抗体
Reelin (RELN)

适用

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  • 13
  • 2

宿主

  • 39
  • 13
  • 2
  • 1
小鼠

克隆类型

  • 32
  • 23
单克隆

标记

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This Reelin antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

RELN-4498
  • 抗原表位

    • 5
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    • 1
    • 1
    • 1
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    • 1
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    • 1
    AA 1796-2115

    原理

    Reelin Antibody / RELN (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    A portion of amino acids 1796-2115 was used as the immunogen for the Reelin antibody.

    亚型

    IgG2b
  • 应用备注

    Optimal dilution of the Reelin antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the Reelin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    Reelin (RELN)

    别名

    Reelin

    背景

    Reelin (or Reln) is a large glycoprotein that is secreted by Cajal-Retzius cells in the forebrain and by granule neurons in the cerebellum. Reelin was shown to be mutated in reeler mice, a mutation that is associated with widespread disruption of laminated regions of the brain, leading to impaired motor coordination, tremors and ataxia. Reelin protein expression is complex and changes throughout development. Reelin appears to function upstream of Dab1, in a signaling pathway that controls cell positioning in the developing brain, and is also thought to be a direct effector of the neurotrophin BDNF.

    UniProt

    P78509

    途径

    Synaptic Membrane
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