Recombinant Villin 1 抗体 (AA 179-311)
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Quick Overview for Recombinant Villin 1 抗体 (AA 179-311) (ABIN7871356)
抗原
See all Villin 1 (VIL1) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 179-311
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原理
- Recombinant Villin Antibody / VIL1
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纯化方法
- Protein A affinity chromatography
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免疫原
- Amino acids 179-311 from the human protein were used as the immunogen for this recombinant Villin antibody.
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亚型
- IgG, kappa
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应用备注
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The stated application concentrations are suggested starting points. Titration of the recombinant Villin antibody may be required due to differences in protocols and secondary/substrate sensitivity.
1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min. -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide, *For IHC use only*
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the recombinant Villin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- Villin 1 (VIL1)
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别名
- Villin
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背景
- Recognizes a protein of 95 kDa, which is identified as villin. It is a major constituent in the microvilli, which compose the brush border of epithelial cells forming absorptive surfaces of the intestinal and renal proximal tubular epithelia. Anti-Villin labels the brush border area in the gastrointestinal mucosal epithelium and urogenital tract. Among neoplasms, villin is predominantly expressed in tumors of colorectal origin. Antibody to villin is useful in identifying malignant cells from primary and metastatic colorectal carcinomas. This antibody also labels Merkel cells of the skin.
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UniProt
- P09327
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途径
- EGFR Signaling Pathway, Regulation of Actin Filament Polymerization
抗原
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