Villin 1 抗体 (AA 179-311)
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Quick Overview for Villin 1 抗体 (AA 179-311) (ABIN7871351)
抗原
See all Villin 1 (VIL1) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- AA 179-311
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原理
- Villin Antibody (azide and preservative free)
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纯化方法
- Protein G affinity chromatography
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免疫原
- A recombinant human partial protein (amino acids 179-311) was used as the immunogen for this Villin antibody.
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亚型
- IgG1, kappa
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应用备注
- Optimal dilution of the Villin antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the Villin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- Villin 1 (VIL1)
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别名
- Villin
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背景
- Recognizes a protein of 95 kDa, which is identified as villin. It is a major constituent in the microvilli, which compose the brush border of epithelial cells forming absorptive surfaces of the intestinal and renal proximal tubular epithelia. Anti-Villin labels the brush border area in the gastrointestinal mucosal epithelium and urogenital tract. Among neoplasms, villin is predominantly expressed in tumors of colorectal origin. Antibody to villin is useful in identifying malignant cells from primary and metastatic colorectal carcinomas. This antibody also labels Merkel cells of the skin.
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UniProt
- P09327
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途径
- EGFR Signaling Pathway, Regulation of Actin Filament Polymerization
抗原
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