MUC4 抗体 (AA 1730-1864)
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Quick Overview for MUC4 抗体 (AA 1730-1864) (ABIN7871280)
抗原
See all MUC4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1730-1864
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原理
- MUC4 Antibody / Mucin-4
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纯化方法
- Protein G affinity chromatography
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免疫原
- Amino acids 1730-1864 from the human protein were used as the immunogen for this MUC4 antibody.
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亚型
- IgG2b, kappa
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anti-Mucin 4, Cell Surface Associated (MUC4) (AA 79-188) antibody
MUC4 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 5B12 unconjugated
anti-Mucin 4, Cell Surface Associated (MUC4) (AA 1730-1864) antibodyMUC4 适用: 人 IHC 宿主: 小鼠 Monoclonal MUC4-3084 unconjugated
anti-Mucin 4, Cell Surface Associated (MUC4) (AA 1730-1864) antibodyMUC4 适用: 人 IHC 宿主: 小鼠 Monoclonal MUC4-3105 unconjugated
anti-Mucin 4, Cell Surface Associated (MUC4) antibodyKD Validated MUC4 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB2595 unconjugated Recombinant Antibody
anti-Mucin 4, Cell Surface Associated (MUC4) (AA 1501-1613) antibodyMUC4 适用: 人, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Mucin 4, Cell Surface Associated (MUC4) (AA 529-560), (N-Term) antibodyMUC4 适用: 人 WB 宿主: 兔 Polyclonal RB49957 unconjugated
anti-Mucin 4, Cell Surface Associated (MUC4) (AA 79-188) antibodyMUC4 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Mucin 4, Cell Surface Associated (MUC4) (AA 1154-1309) antibodyMUC4 适用: 人 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mucin 4, Cell Surface Associated (MUC4) (AA 529-560), (N-Term) antibodyMUC4 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Mucin 4, Cell Surface Associated (MUC4) (AA 1249-1444) antibodyMUC4 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the MUC4 antibody to be titered up or down for optimal performance.
1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the MUC4 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- MUC4 (Mucin 4, Cell Surface Associated (MUC4))
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别名
- MUC4
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背景
- The major constituents of mucus, the viscous secretion that covers epithelial surfaces such as those in the trachea, colon, and cervix, are highly glycosylated proteins called mucins. These glycoproteins play important roles in the protection of the epithelial cells and have been implicated in epithelial renewal and differentiation. This gene encodes an integral membrane glycoprotein found on the cell surface, although secreted isoforms may exist. MUC-4 transcripts have been detected in normal respiratory epithelium and lung. MUC-4 is a very specific (100 % ) and sensitive (90 %) marker of lung adenocarcinomas and is negative for mesotheliomas. Reportedly, MUC-4 expression in invasive ductal carcinoma of the pancreas is an independent factor for poor prognosis.
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UniProt
- Q99102
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途径
- Regulation of Leukocyte Mediated Immunity
抗原
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