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MUC4 抗体 (AA 1730-1864)

This 小鼠 单克隆 antibody specifically detects MUC4 in IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7871279
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for MUC4 抗体 (AA 1730-1864) (ABIN7871279)

抗原

See all MUC4 抗体
MUC4 (Mucin 4, Cell Surface Associated (MUC4))

适用

  • 87
  • 15
  • 5

宿主

  • 53
  • 36
小鼠

克隆类型

  • 66
  • 23
单克隆

标记

  • 57
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This MUC4 antibody is un-conjugated

应用范围

  • 45
  • 35
  • 18
  • 17
  • 13
  • 10
  • 6
  • 6
  • 5
  • 2
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

MUC4-3105
  • 抗原表位

    • 32
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1730-1864

    原理

    MUC4 Antibody / Mucin-4

    纯化方法

    Protein G affinity chromatography

    免疫原

    Amino acids 1730-1864 from the human protein were used as the immunogen for this MUC4 antibody.

    亚型

    IgG2b, kappa
  • 应用备注

    The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the MUC4 antibody to be titered up or down for optimal performance.

    1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide, *For IHC use only*

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store the MUC4 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    MUC4 (Mucin 4, Cell Surface Associated (MUC4))

    别名

    MUC4

    背景

    The major constituents of mucus, the viscous secretion that covers epithelial surfaces such as those in the trachea, colon, and cervix, are highly glycosylated proteins called mucins. These glycoproteins play important roles in the protection of the epithelial cells and have been implicated in epithelial renewal and differentiation. This gene encodes an integral membrane glycoprotein found on the cell surface, although secreted isoforms may exist. MUC-4 transcripts have been detected in normal respiratory epithelium and lung. MUC-4 is a very specific (100 % ) and sensitive (90 %) marker of lung adenocarcinomas and is negative for mesotheliomas. Reportedly, MUC-4 expression in invasive ductal carcinoma of the pancreas is an independent factor for poor prognosis.

    UniProt

    Q99102

    途径

    Regulation of Leukocyte Mediated Immunity
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