PIK3R5 抗体 (AA 170-864)
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Quick Overview for PIK3R5 抗体 (AA 170-864) (ABIN7871254)
抗原
See all PIK3R5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 170-864
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原理
- PIK3R5 Antibody
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纯化方法
- Antigen affinity chromatography
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免疫原
- An E.coli-derived human recombinant protein (amino acids E170-L864) was used as the immunogen for the PIK3R5 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the PIK3R5 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the PIK3R5 Antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- PIK3R5 (Phosphoinositide-3-Kinase, Regulatory Subunit 5 (PIK3R5))
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别名
- PIK3R5
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背景
- Phosphoinositide 3-kinase regulatory subunit 5 is an enzyme that in humans is encoded by the PIK3R5 gene. Phosphatidylinositol 3-kinases (PI3Ks) phosphorylate the inositol ring of phosphatidylinositol at the 3-prime position, and play important roles in cell growth, proliferation, differentiation, motility, survival and intracellular trafficking. The PI3Ks are divided into three classes: I, II and III, and only the class I PI3Ks are involved in oncogenesis. This gene encodes the 101 kD regulatory subunit of the class I PI3K gamma complex, which is a dimeric enzyme, consisting of a 110 kD catalytic subunit gamma and a regulatory subunit of either 55, 87 or 101 kD. This protein recruits the catalytic subunit from the cytosol to the plasma membrane through high-affinity interaction with G-beta-gamma proteins. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found.
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UniProt
- Q8WYR1
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途径
- PI3K-Akt Signaling, Inositol Metabolic Process, Hepatitis C, VEGF Signaling
抗原
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