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ZNF488 抗体 (AA 170-307)

The 小鼠 单克隆 anti-ZNF488 antibody is suitable to detect ZNF488 in samples from 人. It has been validated for FACS 和 IHC (p).
产品编号 ABIN7871250
发货至: 中国
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Quick Overview for ZNF488 抗体 (AA 170-307) (ABIN7871250)

抗原

See all ZNF488 抗体
ZNF488 (Zinc Finger Protein 488 (ZNF488))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This ZNF488 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

PCRP-ZNF488-2D8
  • 抗原表位

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    AA 170-307

    原理

    ZNF488 Antibody

    纯化方法

    Protein A/G affinity

    免疫原

    A recombinant partial protein (within amino acids 170-307) from the human protein was used as the immunogen for the ZNF488 antibody.

    亚型

    IgG2a
  • 应用备注

    Optimal dilution of the ZNF488 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the ZNF488 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    ZNF488 (Zinc Finger Protein 488 (ZNF488))

    别名

    ZNF488

    背景

    Zinc finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc finger proteins contain a Kruppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF488 is a 340 amino acid transcriptional regulator belonging to the Kruppel C2H2-type zinc finger protein family. ZNF488 localizes to the nucleus and contains two C2H2-type zinc fingers. ZNF488 is encoded by a gene located on chromosome 10, which contains a plethora of interesting genes and represents between 4 and 4.5 percent of the total DNA in cells. Jackson-Weiss, Cowden and Usher syndromes are a few diseases related to genes on chromosome 10.

    UniProt

    Q96MN9
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