DLGAP1 抗体 (AA 17-319)
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Quick Overview for DLGAP1 抗体 (AA 17-319) (ABIN7871221)
抗原
See all DLGAP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 17-319
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原理
- DLGAP1 Antibody / DAP-1
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纯化方法
- Affinity purified
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免疫原
- An E. coli-derived human protein (amino acids D17-Q319) was used as the immunogen for the DLGAP1 antibody.
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亚型
- IgG
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anti-Discs, Large (Drosophila) Homolog-Associated Protein 1 (DLGAP1) antibody
DLGAP1 适用: 人 ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 3G4 unconjugated
anti-Discs, Large (Drosophila) Homolog-Associated Protein 1 (DLGAP1) (AA 17-319) antibodyDLGAP1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Discs, Large (Drosophila) Homolog-Associated Protein 1 (DLGAP1) (AA 1-100) antibodyDLGAP1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A6 unconjugated
anti-Discs, Large (Drosophila) Homolog-Associated Protein 1 (DLGAP1) (AA 391-405) antibodyDLGAP1 适用: 人, 大鼠, 小鼠, 犬, Bat, Cow, Hamster, 马, 兔, 非洲爪蟾 IHC, IHC (p) 宿主: 山羊 Polyclonal unconjugated
anti-Discs, Large (Drosophila) Homolog-Associated Protein 1 (DLGAP1) (Internal Region) antibodyDLGAP1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Discs, Large (Drosophila) Homolog-Associated Protein 1 (DLGAP1) (AA 162-190), (N-Term) antibodyDLGAP1 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB19603 unconjugated
anti-Discs, Large (Drosophila) Homolog-Associated Protein 1 (DLGAP1) (C-Term) antibodyDLGAP1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Discs, Large (Drosophila) Homolog-Associated Protein 1 (DLGAP1) (C-Term) antibodyDLGAP1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Discs, Large (Drosophila) Homolog-Associated Protein 1 (DLGAP1) (AA 791-840) antibodyDLGAP1 适用: 人, 大鼠, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Discs, Large (Drosophila) Homolog-Associated Protein 1 (DLGAP1) (AA 397-411), (Intracellular) antibodyDLGAP1 适用: 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the DLGAP1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the DLGAP1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- DLGAP1 (Discs, Large (Drosophila) Homolog-Associated Protein 1 (DLGAP1))
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别名
- DLGAP1
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背景
- Disks large-associated protein 1 (DAP-1), also known as guanylate kinase-associated protein (GKAP), is a protein that in humans is encoded by the DLGAP1 gene. The neurotransmitter glutamate facilitates neuronal signalling at excitatory synapses. Glutamate is released from the presynaptic membrane into the synaptic cleft. Across the synaptic cleft glutamate binds to both ion channels and metabotropic glutamate receptors at the postsynapse, which expedite downstream signalling in the neuron. The postsynaptic density, a highly specialized matrix, which is attached to the postsynaptic membrane, controls this downstream signalling. The postsynaptic density also resets the synapse after each synaptic firing. It is composed of numerous proteins including a family of Discs large associated protein 1, 2, 3 and 4 (DLGAP1-4) that act as scaffold proteins in the postsynaptic density. They link the glutamate receptors in the postsynaptic membrane to other glutamate receptors, to signalling proteins and to components of the cytoskeleton. With the central localisation in the postsynapse, the DLGAP family seems to play a vital role in synaptic scaling by regulating the turnover of both ionotropic and metabotropic glutamate receptors in response to synaptic activity. DLGAP family has been directly linked to a variety of psychological and neurological disorders.
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UniProt
- O14490
抗原
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