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RBM22 抗体 (AA 17-296)

This 兔 多克隆 antibody specifically detects RBM22 in WB. It exhibits reactivity toward 斑马鱼.
产品编号 ABIN7871219
发货至: 中国
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Quick Overview for RBM22 抗体 (AA 17-296) (ABIN7871219)

抗原

See all RBM22 抗体
RBM22 (RNA Binding Motif Protein 22 (RBM22))

适用

  • 44
  • 26
  • 9
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  • 5
  • 5
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  • 1
斑马鱼

宿主

  • 45

克隆类型

  • 45
多克隆

标记

  • 22
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  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This RBM22 antibody is un-conjugated

应用范围

  • 41
  • 18
  • 15
  • 13
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  • 3
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  • 1
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  • 1
Western Blotting (WB)
  • 抗原表位

    • 15
    • 9
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    • 2
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    • 2
    • 2
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    • 1
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    • 1
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    • 1
    AA 17-296

    原理

    Zebrafish Rbm22 Antibody / RNA-binding protein 22

    纯化方法

    Antigen affinity chromatography

    免疫原

    E. coli-derived zebrafish Rbm22 recombinant protein (amino acids D17-R296) was used as the immunogen for the Zebrafish Rbm22 antibody.

    亚型

    Ig Fraction
  • 应用备注

    Optimal dilution of the Zebrafish Rbm22 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the Zebrafish Rbm22 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    RBM22 (RNA Binding Motif Protein 22 (RBM22))

    别名

    Rbm22

    背景

    Zebrafish Rbm22, also known as RNA binding motif protein 22, is a nuclear protein that plays an essential role in pre messenger RNA splicing. It is a component of the spliceosome complex and is critical for the correct processing and maturation of RNA transcripts. Rbm22 contains an RNA recognition motif that enables it to bind RNA and participate in the assembly of spliceosomal complexes during the splicing cycle.

    Zebrafish Rbm22 is an ortholog of the human RBM22 protein and exhibits a high degree of sequence and functional conservation. In both zebrafish and humans, Rbm22 is involved in regulating alternative splicing events that contribute to the diversity of the transcriptome and the regulation of gene expression. Its function is particularly important during early development when precise control of splicing is required for cell differentiation and tissue formation.

    There is currently limited evidence for multiple isoforms of zebrafish Rbm22, although alternative splicing is a common feature of RNA binding proteins, and further studies may reveal additional isoforms in the future. The zebrafish model provides an excellent system to study the conserved roles of Rbm22 in RNA metabolism and developmental processes.

    Antibodies targeting zebrafish Rbm22 protein are valuable for research in RNA biology, splicing regulation, and gene expression studies. Given its orthology to human RBM22, studies using zebrafish Rbm22 can provide insights into conserved mechanisms of splicing regulation and its potential links to human disease.

    UniProt

    Q6NZZ9

    途径

    Protein targeting to Nucleus
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