HPRT1 抗体 (AA 17-186)
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Quick Overview for HPRT1 抗体 (AA 17-186) (ABIN7871211)
抗原
See all HPRT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 17-186
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原理
- HGPRTase Antibody / HPRT1
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纯化方法
- Antigen affinity purified
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免疫原
- E. coli-derived recombinant human protein (amino acids Y17-K186) was used as the immunogen for the HGPRTase antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the HGPRTase antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the HGPRTase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- HPRT1 (Hypoxanthine phosphoribosyltransferase 1 (HPRT1))
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别名
- HGPRTase
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背景
- Hypoxanthine-guanine phosphoribosyltransferase (HGPRT, HGPRTase) is an enzyme encoded in humans by the HPRT1 gene. The protein encoded by this gene is a transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. This enzyme plays a central role in the generation of purine nucleotides through the purine salvage pathway. Mutations in this gene result in Lesch-Nyhan syndrome or gout.
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UniProt
- P00492
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途径
- Ribonucleoside Biosynthetic Process
抗原
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