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DDIT3 抗体 (AA 17-168)

Name: DDIT3 抗体 (AA 17-168)
SKU: ABIN7871209
Availability: OutOfStock

The 兔多克隆 anti-DDIT3 antibody (ABIN7871209) specifically detects DDIT3 in WB, ELISA 和 FACS. The antibody is reactive with 小鼠和大鼠 samples.

产品编号 ABIN7871209

发货至: 中国

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Quick Overview for DDIT3 抗体 (AA 17-168) (ABIN7871209)

抗原

See all DDIT3 抗体

DDIT3 (DNA-Damage-Inducible Transcript 3 (DDIT3))

适用

小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This DDIT3 antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Discover our top product DDIT3 Primary Antibody

抗原表位
16

16

12

11

10

7

7

7

4

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 17-168

原理

Ddit3 Antibody / Chop / Gadd153

纯化方法

Affinity purified

免疫原

An E. coli-derived mouse protein (amino acids E17-A168) was used as the immunogen for the Ddit3 antibody.

亚型

IgG
anti-DNA-Damage-Inducible Transcript 3 (DDIT3) (C-Term) antibody
DDIT3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-DNA-Damage-Inducible Transcript 3 (DDIT3) (AA 120-149), (C-Term) antibody
DDIT3 适用: 人, 小鼠 WB, IF, FACS 宿主: 兔 Polyclonal RB13788 unconjugated

anti-DNA-Damage-Inducible Transcript 3 (DDIT3) (AA 1-169) antibody
DDIT3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-DNA-Damage-Inducible Transcript 3 (DDIT3) (N-Term) antibody
DDIT3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-DNA-Damage-Inducible Transcript 3 (DDIT3) (pSer30) antibody
DDIT3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-DNA-Damage-Inducible Transcript 3 (DDIT3) (N-Term) antibody
DDIT3 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-DNA-Damage-Inducible Transcript 3 (DDIT3) (AA 1-169) antibody
DDIT3 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-DNA-Damage-Inducible Transcript 3 (DDIT3) (Ser301) antibody
DDIT3 适用: 人, 小鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-DNA-Damage-Inducible Transcript 3 (DDIT3) (AA 1-90) antibody
DDIT3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2G3 unconjugated

anti-DNA-Damage-Inducible Transcript 3 (DDIT3) antibody
KD Validated DDIT3 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB2955 unconjugated Recombinant Antibody

应用备注

Optimal dilution of the Ddit3 antibody should be determined by the researcher.

限制

仅限研究用
状态

Lyophilized

缓冲液

0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

储存条件

4 °C,-20 °C

储存方法

After reconstitution, the Ddit3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
抗原

DDIT3 (DNA-Damage-Inducible Transcript 3 (DDIT3))

别名

Ddit3

背景

DNA damage-inducible transcript 3, also known as C/EBP homologous protein (CHOP), is a pro-apoptotic transcription factor that is encoded by the DDIT3 gene. It is mapped to 12q13.3. This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified.

UniProt

P35639

途径

Regulation of Muscle Cell Differentiation, ER-Nucleus Signaling, Skeletal Muscle Fiber Development, Cell RedoxHomeostasis