MOV10 抗体 (AA 167-772)
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北京 101111
Quick Overview for MOV10 抗体 (AA 167-772) (ABIN7871196)
抗原
See all MOV10 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 167-772
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原理
- MOV10 Antibody
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids H167-Q772) was used as the immunogen for the MOV10 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the MOV10 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the MOV10 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- MOV10 (Moloney Leukemia Virus 10 (MOV10))
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别名
- MOV10
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背景
- Putative helicase MOV-10 is an enzyme that in humans is encoded by the MOV10 gene. MOV10, also named as KIAA1631, belongs to the DNA2/NAM7 helicase family and SDE3 subfamily. It is required for RNA-mediated gene silencing by the RNA-induced silencing complex (RISC). Human MOV10 may regulate a wide range of RNA viruses and could also control the retro-transposition of endogenous retroelements in mammals. MOV10 has a broad antiretroviral activity that can target a wide range of retroviruses, and it could be actively involved in host defense against retroviral infection. MOV10 can potently inhibit HIV-1 replication at multiple stages. It is involved in the progression of telomerase-catalyzing reaction via the interaction of telomerase protein and telomere DNA.
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UniProt
- Q9HCE1
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途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, SARS-CoV-2 Protein Interactome
抗原
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