TLN1 抗体 (AA 1658-1876)
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Quick Overview for TLN1 抗体 (AA 1658-1876) (ABIN7871151)
抗原
See all TLN1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1658-1876
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原理
- TLN1 Antibody / Talin 1
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human Talin 1/TLN1 protein (amino acids Q1658-N1876) was used as the immunogen for the TLN1 antibody.
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亚型
- IgG1
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应用备注
- Optimal dilution of the TLN1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the TLN1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- TLN1 (Talin 1 (TLN1))
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别名
- TLN1
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背景
- Talin-1 is a protein that in humans is encoded by the TLN1 gene. This gene encodes a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts. The encoded protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminus contains binding sites for proteins such as beta-1-integrin, actin, and vinculin.
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UniProt
- Q9Y490
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途径
- Cell-Cell Junction Organization, ER-Nucleus Signaling, Maintenance of Protein Location
抗原
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