SRF 抗体 (AA 163-508)
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Quick Overview for SRF 抗体 (AA 163-508) (ABIN7871127)
抗原
See all SRF 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 163-508
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原理
- SRF Antibody / Serum Response Factor
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纯化方法
- Affinity purified
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免疫原
- An E. coli-derived human protein (amino acids K163-E508) was used as the immunogen for the SRF antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the SRF antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the SRF antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- SRF (Serum Response Factor (SRF))
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别名
- SRF
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背景
- Serum response factor, also known as SRF, is a transcription factor protein. This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways, for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs). Two transcript variants encoding different isoforms have been found for this gene.
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UniProt
- P11831
抗原
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