IRF4 抗体 (AA 163-419)
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北京 101111
Quick Overview for IRF4 抗体 (AA 163-419) (ABIN7871126)
抗原
See all IRF4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 163-419
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原理
- Interferon regulatory factor 4 Antibody / IRF4 / MUM1
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纯化方法
- Antigen affinity chromatography
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免疫原
- An E.coli-derived human recombinant protein (amino acids A163-Q419) was used as the immunogen for the Interferon regulatory factor 4 antibody.
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亚型
- IgG
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anti-Interferon Regulatory Factor 4 (IRF4) (AA 342-451) antibody
IRF4 适用: 人 WB, ELISA, IF, RNAi 宿主: 小鼠 Monoclonal 2D1 unconjugated
anti-Interferon Regulatory Factor 4 (IRF4) (AA 342-451) antibodyIRF4 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2F2 unconjugated
anti-Interferon Regulatory Factor 4 (IRF4) (AA 393-407) antibodyVerified IRF4 适用: 人, 大鼠 WB, ELISA, IHC, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Interferon Regulatory Factor 4 (IRF4) (AA 342-452) antibodyIRF4 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2F2 unconjugated
anti-Interferon Regulatory Factor 4 (IRF4) (C-Term) antibodyIRF4 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 4 (IRF4) (AA 272-451) antibodyIRF4 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 4 (IRF4) (AA 342-452) antibodyIRF4 适用: 人 WB, IHC (p), EIA 宿主: 小鼠 Monoclonal 2F2 unconjugated
anti-Interferon Regulatory Factor 4 (IRF4) (N-Term) antibodyIRF4 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, Cow, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 4 (IRF4) (AA 175-433) antibodyIRF4 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 4 (IRF4) (C-Term) antibodyVerified IRF4 适用: 人, 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
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应用备注
- Optimal dilution of the Interferon regulatory factor 4 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Interferon regulatory factor 4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- IRF4 (Interferon Regulatory Factor 4 (IRF4))
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别名
- Interferon regulatory factor 4
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背景
- Interferon regulatory factor 4 (IRF4), also known as Multiple myeloma oncogene 1 (MUM1), is a protein that in humans is encoded by the IRF4 gene. It is located on 6p25.3. IRF4 is a transcription factor, and it is essential for the development of T helper-2 (Th2) cells, IL17 -producing Th17 cells, and IL9 -producing Th9 cells. In melanocytic cells, the IRF4 gene may be regulated by MITF. IRF4 is a transcription factor that has been implicated in acute leukemia. This gene is strongly associated with pigmentation, sensitivity of skin to sun exposure, freckles, blue eyes, and brown hair color. What's more, IRF4 inhibition is toxic to myeloma cell lines, regardless of transforming oncogenic mechanism.
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UniProt
- Q15306
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途径
- Chromatin Binding
抗原
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