AFG3L2 抗体 (AA 161-245)
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Quick Overview for AFG3L2 抗体 (AA 161-245) (ABIN7871108)
抗原
See all AFG3L2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 161-245
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原理
- Zebrafish Afg3l2 Antibody / AFG3 like protein 2
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纯化方法
- Antigen affinity chromatography
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免疫原
- An E.coli-derived zebrafish Afg3l2 recombinant protein (amino acids G161-D245) was used as the immunogen for the Zebrafish Afg3l2 antibody.
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亚型
- Ig Fraction
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应用备注
- Optimal dilution of the Zebrafish Afg3l2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Zebrafish Afg3l2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- AFG3L2 (AFG3-Like Protein 2 (AFG3L2))
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别名
- Afg3l2
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背景
- AFG3L2 is the catalytic subunit of the m-AAA protease, an ATP-dependent proteolytic complex of the mitochondrial inner membrane that degrades misfolded proteins and regulates ribosome assembly. In humans, it is encoded by the AFG3L2 gene. This gene encodes a protein localized in mitochondria and closely related to paraplegin. The paraplegin gene is responsible for an autosomal recessive form of hereditary spastic paraplegia. And this gene is a candidate gene for other hereditary spastic paraplegias or neurodegenerative disorders as well as spastic ataxia-neuropathy syndrome.
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UniProt
- A9JRG9
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途径
- Skeletal Muscle Fiber Development
抗原
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