Neurofibromin 1 抗体 (AA 160-270)
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Quick Overview for Neurofibromin 1 抗体 (AA 160-270) (ABIN7871101)
抗原
See all Neurofibromin 1 (NF1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 160-270
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原理
- Neurofibromin Antibody / NF1
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids R160-Q270) was used as the immunogen for the Neurofibromin antibody.
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亚型
- IgG2b
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应用备注
- Optimal dilution of the Neurofibromin antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Neurofibromin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- Neurofibromin 1 (NF1)
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别名
- Neurofibromin
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背景
- Neurofibromin 1 (NF1) is a gene in humans that is located on chromosome 17. This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene.
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UniProt
- P21359
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途径
- cAMP Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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