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Neurofibromin 1 抗体 (AA 160-270)

The 小鼠 单克隆 anti-Neurofibromin 1 antibody is suitable to detect Neurofibromin 1 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, IF, IHC (p) 和 FACS.
产品编号 ABIN7871100
发货至: 中国
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Quick Overview for Neurofibromin 1 抗体 (AA 160-270) (ABIN7871100)

抗原

See all Neurofibromin 1 (NF1) 抗体
Neurofibromin 1 (NF1)

适用

  • 70
  • 55
  • 37
  • 2
  • 2
  • 2
  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 77
  • 9
小鼠

克隆类型

  • 75
  • 11
单克隆

标记

  • 34
  • 5
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Neurofibromin 1 antibody is un-conjugated

应用范围

  • 39
  • 39
  • 28
  • 26
  • 16
  • 14
  • 12
  • 9
  • 9
  • 7
  • 5
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

克隆位点

4F8B7
  • 抗原表位

    • 15
    • 15
    • 15
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 160-270

    原理

    NF1 Antibody / Neurofibromin

    纯化方法

    Affinity purified

    免疫原

    Recombinant human protein (amino acids R160-Q270) was used as the immunogen for the NF1 antibody.

    亚型

    IgG2a
  • 应用备注

    Optimal dilution of the NF1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the NF1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    Neurofibromin 1 (NF1)

    别名

    NF1

    背景

    Neurofibromin 1 (NF1) is a gene in humans that is located on chromosome 17. This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene.

    UniProt

    P21359

    途径

    cAMP Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity
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