SF3A1 抗体 (AA 16-646)
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Quick Overview for SF3A1 抗体 (AA 16-646) (ABIN7871091)
抗原
See all SF3A1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 16-646
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原理
- Zebrafish Sf3a1 Antibody / Splicing factor 3A subunit 1
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纯化方法
- Antigen affinity chromatography
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免疫原
- E. coli-derived zebrafish Sf3a1 recombinant protein (amino acids K16-P646) was used as the immunogen for the Zebrafish Sf3a1 antibody.
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亚型
- Ig Fraction
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anti-Splicing Factor 3a, Subunit 1 (SF3A1) (AA 249-568) antibody
SF3A1 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 4D8 unconjugated
anti-Splicing Factor 3a, Subunit 1 (SF3A1) (AA 20-556) antibodySF3A1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ELISA, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Splicing Factor 3a, Subunit 1 (SF3A1) (AA 300-350) antibodySF3A1 适用: 人, 小鼠 IHC, IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Splicing Factor 3a, Subunit 1 (SF3A1) (N-Term) antibodySF3A1 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 斑马鱼, 豚鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Splicing Factor 3a, Subunit 1 (SF3A1) (AA 249-568) antibodySF3A1 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 8H1 unconjugated
anti-Splicing Factor 3a, Subunit 1 (SF3A1) (AA 443-793) antibodySF3A1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Splicing Factor 3a, Subunit 1 (SF3A1) (AA 1-793) antibodySF3A1 适用: 人, 小鼠, 大鼠, 哺乳动物 WB, IHC, IP, IHC (p), ICC 宿主: 小鼠 Monoclonal 85D5 unconjugated
anti-Splicing Factor 3a, Subunit 1 (SF3A1) (AA 140-227) antibodySF3A1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Splicing Factor 3a, Subunit 1 (SF3A1) (N-Term) antibodySF3A1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Splicing Factor 3a, Subunit 1 (SF3A1) (AA 249-568) antibodySF3A1 适用: 人 WB 宿主: 小鼠 Monoclonal 7G6 unconjugated
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应用备注
- Optimal dilution of the Zebrafish Sf3a1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Zebrafish Sf3a1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- SF3A1 (Splicing Factor 3a, Subunit 1 (SF3A1))
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别名
- Sf3a1
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背景
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Zebrafish Sf3a1, also known as splicing factor 3A subunit 1, is a critical component of the spliceosome complex that regulates the removal of introns from pre messenger RNA. Sf3a1 is part of the SF3A protein complex, which works together with the SF3B complex to stabilize the binding of the U2 small nuclear ribonucleoprotein to the branch point sequence during splicing. This step is essential for accurate and efficient splicing, which in turn is vital for the generation of mature and functional messenger RNA transcripts.
Zebrafish Sf3a1 is an ortholog of the human SF3A1 protein and shares significant sequence and functional conservation. Like its human counterpart, zebrafish Sf3a1 is required for normal RNA processing and proper regulation of gene expression. Due to the importance of splicing in controlling developmental and cellular processes, Sf3a1 function is essential during embryogenesis and tissue differentiation.
Currently, there are no known isoforms of zebrafish Sf3a1 that have been characterized, but as with other splicing factors, alternative splicing may generate additional transcript variants that are yet to be fully studied. Research into zebrafish Sf3a1 offers valuable insights into conserved mechanisms of splicing regulation and its roles in development and disease.
Antibodies targeting zebrafish Sf3a1 protein are useful tools for examining spliceosomal assembly, RNA processing, and transcriptional regulation. These antibodies are commonly used in applications such as western blot, immunohistochemistry, immunofluorescence, and ELISA, supporting a broad range of molecular and developmental biology studies.
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UniProt
- Q90X41
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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