NDFIP2 抗体 (AA 16-336)
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Quick Overview for NDFIP2 抗体 (AA 16-336) (ABIN7871068)
抗原
See all NDFIP2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 16-336
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原理
- NDFIP2 Antibody / NEDD4 family-interacting protein 2
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids M16-L336) was used as the immunogen for the NDFIP2 antibody.
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亚型
- IgG2b
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应用备注
- Optimal dilution of the NDFIP2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the NDFIP2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- NDFIP2 (Nedd4 Family Interacting Protein 2 (NDFIP2))
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别名
- NDFIP2
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背景
- NEDD4 family-interacting protein 2 is a protein that in humans is encoded by the NDFIP2 gene. The NEDD4 family-interacting protein 1 (NDFIP1) belongs to a small group of evolutionarily conserved proteins with three transmembrane domains and is an integral Golgi membrane protein. It is a potential target for ubiquitination by the Nedd4 family of proteins. NDFIP1 is strongly expressed in surviving neurons following acute cortical brain injury, and overexpression in cultured cortical neurons increased survival following growth factor starvation, suggesting that NDFIP1 may play a role in neuronal survival. NDFIP1 and the related protein NDFIP2 are thought to interact with and regulate multiple components of the EGF and PTEN/Akt signaling pathways. Recent studies suggest that NDFIP1 may also play a role in Th17 differentiation by limiting the production of proinflammatory cytokines.
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UniProt
- Q9NV92
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途径
- Negative Regulation of Transporter Activity, SARS-CoV-2 Protein Interactome
抗原
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