TRIP4 抗体 (AA 158-563)
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Quick Overview for TRIP4 抗体 (AA 158-563) (ABIN7871028)
抗原
See all TRIP4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 158-563
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原理
- ASC1 Antibody / TRIP-4
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纯化方法
- Antigen affinity purified
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免疫原
- E. coli-derived recombinant human protein (amino acids Q158-D563) was used as the immunogen for the ASC1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the ASC1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the ASC1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- TRIP4 (Thyroid Hormone Receptor Interactor 4 (TRIP4))
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别名
- ASC1
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背景
- Activating signal cointegrator 1 is a protein that in humans is encoded by the TRIP4 gene. This gene encodes a subunit of the tetrameric nuclear activating signal cointegrator 1 (ASC-1) complex, which associates with transcriptional coactivators, nuclear receptors and basal transcription factors to facilitate nuclear receptors-mediated transcription. This protein is localized in the nucleus and contains an E1A-type zinc finger domain, which mediates interaction with transcriptional coactivators and ligand-bound nuclear receptors, such as thyroid hormone receptor and retinoid X receptor alpha, but not glucocorticoid receptor. Mutations in this gene are associated with spinal muscular atrophy with congenital bone fractures-1 (SMABF1).
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UniProt
- Q15650
抗原
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