RAB7A 抗体 (AA 156-197)
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Quick Overview for RAB7A 抗体 (AA 156-197) (ABIN7871017)
抗原
See all RAB7A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 156-197
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原理
- RAB7A Antibody
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纯化方法
- Antigen affinity purified
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免疫原
- An E.coli-derived human recombinant protein (A156-R197) was used as the immunogen for the RAB7A antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the RAB7A antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the RAB7A antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- RAB7A (RAB7A, Member RAS Oncogene Family (RAB7A))
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别名
- RAB7A
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背景
- Ras-related protein Rab-7a is a protein that in humans is encoded by the RAB7A gene. RAB7A functions as a key regulator in endo-lysosomal trafficking, governs early-to-late endosomal maturation, microtubule minus-end as well as plus-end directed endosomal migration and positions, and endosome-lysosome transport through different protein-protein interaction cascades. Furthermore, RAB7A is involved in regulation of some specialized endosomal membrane trafficking, such as maturation of melanosomes through modulation of SOX10 and the oncogene MYC. Mutations in the lysosomal pathway result in tumor progression in melanoma cells.
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UniProt
- P51149
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途径
- EGFR Signaling Pathway, Maintenance of Protein Location, SARS-CoV-2 Protein Interactome
抗原
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