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PCBP1 抗体 (AA 152-268)

The 兔 多克隆 anti-PCBP1 antibody is suitable to detect PCBP1 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, ELISA, IHC (p) 和 FACS.
产品编号 ABIN7870977
发货至: 中国
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Quick Overview for PCBP1 抗体 (AA 152-268) (ABIN7870977)

抗原

See all PCBP1 抗体
PCBP1 (Poly(rC) Binding Protein 1 (PCBP1))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This PCBP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
  • 抗原表位

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    AA 152-268

    原理

    PCBP1 Antibody

    纯化方法

    Affinity purified

    免疫原

    A human recombinant partial protein (amino acids P152-K268) was used as the immunogen for the PCBP1 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the PCBP1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the PCBP1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    PCBP1 (Poly(rC) Binding Protein 1 (PCBP1))

    别名

    PCBP1

    背景

    Poly(rC)-binding protein 1 is a protein that in humans is encoded by the PCBP1 gene. This intronless gene is thought to have been generated by retrotransposition of a fully processed PCBP-2 mRNA. This gene and PCBP-2 have paralogues (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. The protein encoded by this gene appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly(rC)-binding protein. It contains three K-homologous (KH) domains which may be involved in RNA binding. This encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability.

    UniProt

    Q15365
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