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Recombinant SATB2 抗体 (AA 150-350)

The 兔 单克隆 anti-SATB2 antibody (Clone SATB2-8292R) (ABIN7870942) specifically detects SATB2 in IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7870942
发货至: 中国
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Quick Overview for Recombinant SATB2 抗体 (AA 150-350) (ABIN7870942)

抗原

See all SATB2 抗体
SATB2 (SATB Homeobox 2 (SATB2))

抗体类型

Recombinant Antibody

适用

  • 141
  • 46
  • 40
  • 1
  • 1
  • 1
  • 1

宿主

  • 104
  • 37

克隆类型

  • 95
  • 46
单克隆

标记

  • 93
  • 6
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SATB2 antibody is un-conjugated

应用范围

  • 81
  • 62
  • 29
  • 26
  • 16
  • 15
  • 14
  • 13
  • 13
  • 8
  • 3
  • 3
  • 2
  • 1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

SATB2-8292R
  • 抗原表位

    • 33
    • 17
    • 16
    • 8
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 150-350

    原理

    SATB2 Antibody (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    A recombinant partial protein sequence (within amino acids 150-350) from the human protein was used as the immunogen for the SATB2 antibody.

    亚型

    IgG, kappa
  • 应用备注

    Optimal dilution of the SATB2 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the SATB2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    SATB2 (SATB Homeobox 2 (SATB2))

    别名

    SATB2

    背景

    SATB2 is a DNA binding protein that specifically binds nuclear matrix attachment regions. It is involved in transcription regulation and chromatin remodeling. SATB2 expression in colorectal carcinomas (CRC) is correlated with good prognosis and in laryngeal squamous cell carcinoma it functions as a tumor suppressor wherein loss of expression is positively correlated with high tumor grade and recurrence. Moreover, SATB2, in combination with CK20, could identify almost all CRC s. Upper gastrointestinal (GI) carcinomas and pancreatic ductal carcinomas are usually negative for SATB2, and ovarian carcinomas, lung adenocarcinomas, and adenocarcinomas from other origin are rarely positive for SATB2. Additionally, SATB2 antibody can identify neuroendocrine neoplasms of colon and rectum because SATB2 is usually negative in neuroendocrine neoplasms of the GI tract, pancreas, and lung. More recently, it has been reported that SATB2 is a sensitive marker for tumors with osteoblastic differentiation.

    UniProt

    Q9UPW6
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