GBX2 抗体 (AA 150-350)
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北京 101111
Quick Overview for GBX2 抗体 (AA 150-350) (ABIN7870925)
抗原
See all GBX2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 150-350
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原理
- GBX2 Antibody / Gastrulation Brain Homeobox 2
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纯化方法
- Protein A/G affinity
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免疫原
- A recombinant partial protein sequence (within amino acids 150-350) from the human protein was used as the immunogen for the GBX2 antibody.
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亚型
- IgG2, kappa
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anti-Gastrulation Brain Homeo Box 2 (GBX2) (Internal Region) antibody
Verified GBX2 适用: 人 ELISA, IHC, IF 宿主: 山羊 Polyclonal unconjugated
anti-Gastrulation Brain Homeo Box 2 (GBX2) (AA 114-182) antibodyGBX2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2A4 unconjugated
anti-Gastrulation Brain Homeo Box 2 (GBX2) (AA 114-182) antibodyGBX2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A7 unconjugated
anti-Gastrulation Brain Homeo Box 2 (GBX2) (AA 65-248) antibodyGBX2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Gastrulation Brain Homeo Box 2 (GBX2) (AA 181-230) antibodyGBX2 适用: 人, 大鼠, 小鼠, 犬, Cow, 马, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Gastrulation Brain Homeo Box 2 (GBX2) (AA 141-230) antibodyGBX2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3B6 unconjugated
anti-Gastrulation Brain Homeo Box 2 (GBX2) (AA 114-182) antibodyGBX2 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 1C11 unconjugated
anti-Gastrulation Brain Homeo Box 2 (GBX2) (AA 103-131) antibodyGBX2 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-Gastrulation Brain Homeo Box 2 (GBX2) (AA 1-250) antibodyGBX2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Gastrulation Brain Homeo Box 2 (GBX2) (AA 179-228) antibodyGBX2 适用: 人, 大鼠, 小鼠, 兔, 豚鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the GBX2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the GBX2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- GBX2 (Gastrulation Brain Homeo Box 2 (GBX2))
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别名
- GBX2
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背景
- The isthmic organizer signals at the mid/hindbrain boundary (MHB) regulate the development and differentiation of the vertebrate caudal midbrain and the anterior hindbrain. The MHB forms at the boundary of expression between homeobox genes GBX2 and OTX2. GBX2 and OTX2 play distinct, essential roles in MHB positioning and development. During development, the GBX2 gene is expressed in the anterior hindbrain. Specifically, GBX2 negatively regulates OTX2 expression along the anterior-posterior axis, GBX2- mutants demonstrate an expanded OTX2 domain. During development, the GBX2 gene is expressed in the anterior hindbrain. GBX2 is expressed in the adult brain, spleen and female genital tract. The GBX2 gene is overexpressed in human prostate cancer cell lines (TSU-prl, PC3, DU145 and LNCaP). Furthermore, downregulation of GBX2 expression restricts tumorigenicity in human prostate cancer cell lines, which suggests that GBX2 expression may be required for growth of malignant prostate cells.
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UniProt
- P52951
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途径
- Dopaminergic Neurogenesis
抗原
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