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Recombinant PAX8 抗体 (AA 150-300)

The 兔 单克隆 anti-PAX8 antibody is suitable to detect PAX8 in samples from 人. It has been validated for IHC (p).
产品编号 ABIN7870914
发货至: 中国
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Quick Overview for Recombinant PAX8 抗体 (AA 150-300) (ABIN7870914)

抗原

See all PAX8 抗体
PAX8 (Paired Box 8 (PAX8))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This PAX8 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

PAX8-6848R
  • 抗原表位

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    AA 150-300

    原理

    Paired box protein Pax-8 Antibody / PAX8 (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    A recombinant partial protein sequence (within amino acids 150-300) from the human protein was used as the immunogen for the Paired box protein Pax-8 antibody.

    亚型

    IgG, kappa
  • 应用备注

    Optimal dilution of the Paired box protein Pax-8 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the Paired box protein Pax-8 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    PAX8 (Paired Box 8 (PAX8))

    别名

    Paired box protein Pax-8

    背景

    Recognizes a protein of 62 kDa, identified as PAX8. It is a member of the paired box (PAX) family of transcription factors. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas, and atypical thyroid adenomas. PAX-8 is expressed in the thyroid (and associated carcinomas), non-ciliated mucosal cells of the fallopian tubes, and simple ovarian inclusion cysts, but not normal ovarian surface epithelial cells. PAX-8 is expressed in a high percentage of ovarian serous, endometrioid, and clear cell carcinomas, but only rarely in primary ovarian mucinous adenocarcinomas. PAX-8 expression is reported in renal tubules as well as renal cell carcinoma, nephroblastoma, and seminoma. PAX-8 antibody may be used as an additional immunohistochemical marker for renal epithelial tumors.

    UniProt

    Q06710

    途径

    Thyroid Hormone Synthesis, Regulation of Hormone Metabolic Process, Stem Cell Maintenance, Tube Formation
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