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DBN1 抗体 (AA 150-281)

The 小鼠 单克隆 anti-DBN1 antibody is suitable to detect DBN1 in samples from 人. It has been validated for WB 和 IHC (p).
产品编号 ABIN7870875
发货至: 中国
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Quick Overview for DBN1 抗体 (AA 150-281) (ABIN7870875)

抗原

See all DBN1 抗体
DBN1 (Drebrin 1 (DBN1))

适用

  • 75
  • 35
  • 35
  • 3
  • 2
  • 2

宿主

  • 45
  • 30
  • 2
小鼠

克隆类型

  • 42
  • 35
单克隆

标记

  • 37
  • 3
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  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
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  • 1
  • 1
  • 1
  • 1
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This DBN1 antibody is un-conjugated

应用范围

  • 66
  • 19
  • 19
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  • 15
  • 13
  • 13
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  • 8
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  • 1
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  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

DBN1-2879
  • 抗原表位

    • 19
    • 15
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    AA 150-281

    原理

    Drebrin 1 Antibody

    纯化方法

    Protein G affinity chromatography

    免疫原

    A recombinant human partial protein (amino acids 150-281) was used as the immunogen for the Drebrin 1 antibody.

    亚型

    IgG1, kappa
  • 应用备注

    Optimal dilution of the Drebrin 1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store the Drebrin 1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    DBN1 (Drebrin 1 (DBN1))

    别名

    Drebrin 1

    背景

    Drebrins (developmentally regulated brain proteins) are cytoplasmic proteins that bind F-actin in the brain and are involved in cell migration, extension of neuronal processes and plasticity of dendrites. There are three isoforms: two embryonic types (E1 and E2), and an adult type (A), generated by alternative RNA splicing from a single Drebrin gene. Drebrins are expressed mainly in brain neurons but are also found in skeletal muscle, heart, placenta, pancreas and kidney. Drebrin has been designated as a marker of the dendritic spine. Decreases in Drebrin levels in the brain have been been associated with Alzheimer s disease and Down syndrome.

    UniProt

    Q16643

    途径

    Maintenance of Protein Location
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