DBN1 抗体 (AA 150-281)
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Quick Overview for DBN1 抗体 (AA 150-281) (ABIN7870874)
抗原
See all DBN1 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- AA 150-281
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原理
- Drebrin 1 Antibody (azide and preservative free)
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纯化方法
- Protein G affinity chromatography
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免疫原
- A recombinant human partial protein (amino acids 150-281) was used as the immunogen for the Drebrin 1 antibody.
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亚型
- IgG1, kappa
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应用备注
- Optimal dilution of the Drebrin 1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the Drebrin 1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- DBN1 (Drebrin 1 (DBN1))
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别名
- Drebrin 1
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背景
- Drebrins (developmentally regulated brain proteins) are cytoplasmic proteins that bind F-actin in the brain and are involved in cell migration, extension of neuronal processes and plasticity of dendrites. There are three isoforms: two embryonic types (E1 and E2), and an adult type (A), generated by alternative RNA splicing from a single Drebrin gene. Drebrins are expressed mainly in brain neurons but are also found in skeletal muscle, heart, placenta, pancreas and kidney. Drebrin has been designated as a marker of the dendritic spine. Decreases in Drebrin levels in the brain have been been associated with Alzheimer s disease and Down syndrome.
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UniProt
- Q16643
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途径
- Maintenance of Protein Location
抗原
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