POT1 抗体 (AA 15-638)
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Quick Overview for POT1 抗体 (AA 15-638) (ABIN7870800)
抗原
See all POT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 15-638
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原理
- POT1 Antibody
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纯化方法
- Affinity purified
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免疫原
- Recombinant rat protein (amino acids N15-V638) was used as the immunogen for the POT1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the POT1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the POT1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- POT1 (Protection of Telomeres 1 (POT1))
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别名
- POT1
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背景
- Protection of telomeres protein 1 is a protein that in humans is encoded by the POT1 gene. This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described.
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途径
- Cell Division Cycle, Telomere Maintenance
抗原
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