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Transgelin 抗体 (AA 15-170)

The 兔 多克隆 anti-Transgelin antibody is suitable to detect Transgelin in samples from 人, 小鼠 和 大鼠. It has been validated for WB, ELISA, FACS, IHC (p) 和 IF.
产品编号 ABIN7870782
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Transgelin 抗体 (AA 15-170) (ABIN7870782)

抗原

See all Transgelin (TAGLN) 抗体
Transgelin (TAGLN)

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This Transgelin antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
  • 抗原表位

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    AA 15-170

    原理

    TAGLN Antibody / Transgelin / SM22 alpha

    纯化方法

    Antigen affinity purified

    免疫原

    Recombinant human protein (amino acids Q15-E170) was used at the immunogen for the TAGLN antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the TAGLN antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the TAGLN antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    Transgelin (TAGLN)

    别名

    TAGLN

    背景

    Transgelin, also known as SM22 alpha, is a protein that in humans is encoded by the TAGLN gene. This gene encodes a shape change and transformation sensitive actin-binding protein which belongs to the calponin family. It is ubiquitously expressed in vascular and visceral smooth muscle, and is an early marker of smooth muscle differentiation. The encoded protein is thought to be involved in calcium-independent smooth muscle contraction. It acts as a tumor suppressor, and the loss of its expression is an early event in cell transformation and the development of some tumors, coinciding with cellular plasticity. The encoded protein has a domain architecture consisting of an N-terminal calponin homology (CH) domain and a C-terminal calponin-like (CLIK) domain. Mice with a knockout of the orthologous gene are viable and fertile but their vascular smooth muscle cells exhibit alterations in the distribution of the actin filament and changes in cytoskeletal organization.

    UniProt

    Q01995
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