PNPLA6 抗体 (AA 15-1296)
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Quick Overview for PNPLA6 抗体 (AA 15-1296) (ABIN7870780)
抗原
See all PNPLA6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 15-1296
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原理
- PNPLA6 Antibody / NTE
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纯化方法
- Antigen affinity purified
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免疫原
- E. coli-derived recombinant human protein (amino acids H15-E1296) was used as the immunogen for the PNPLA6 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the PNPLA6 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the PNPLA6 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- PNPLA6 (Patatin-Like phospholipase Domain Containing 6 (PNPLA6))
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别名
- PNPLA6
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背景
- Neuropathy target esterase (NTE), also known as patatin-like phospholipase domain-containing protein 6 (PNPLA6), is an esterase enzyme that in humans is encoded by the PNPLA6 gene. This gene encodes a phospholipase that deacetylates intracellular phosphatidylcholine to produce glycerophosphocholine. It is thought to function in neurite outgrowth and process elongation during neuronal differentiation. The protein is anchored to the cytoplasmic face of the endoplasmic reticulum in both neurons and non-neuronal cells. Mutations in this gene result in autosomal recessive spastic paraplegia, and the protein is the target for neurodegeneration induced by organophosphorus compounds and chemical warfare agents. Multiple transcript variants encoding different isoforms have been found for this gene.
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UniProt
- Q8IY17
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途径
- Ribonucleoside Biosynthetic Process
抗原
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