Cadherin 13 抗体 (AA 149-692)
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Quick Overview for Cadherin 13 抗体 (AA 149-692) (ABIN7870778)
抗原
See all Cadherin 13 (CDH13) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 149-692
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原理
- Cadherin 13 Antibody / CDH13 / H Cadherin
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纯化方法
- Affinity purified
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免疫原
- A human recombinant partial protein (amino acids E149-A692) was used as the immunogen for the Cadherin 13 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Cadherin 13 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Cadherin 13 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- Cadherin 13 (CDH13)
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别名
- Cadherin 13
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背景
- H-cadherin (CDH13) is a unique member of cadherin superfamily because it lacks the transmembrane and cytoplasmic domains and is anchored to the cells membrane through the GPI anchor. This protein acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from apoptosis due to oxidative stress, and is associated with resistance to atherosclerosis. The gene is hypermethylated in many types of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.
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UniProt
- P55290
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途径
- EGFR Signaling Pathway, Cell-Cell Junction Organization
抗原
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