TIAM1 抗体 (AA 1478-1506)
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Quick Overview for TIAM1 抗体 (AA 1478-1506) (ABIN7870747)
抗原
See all TIAM1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1478-1506
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原理
- TIAM1 Antibody / T cell lymphoma invasion and metastasis 1
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纯化方法
- Antigen affinity
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免疫原
- A portion of amino acids 1478-1506 from the human protein was used as the immunogen for the TIAM1 antibody.
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亚型
- Ig Fraction
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anti-T-Cell Lymphoma Invasion and Metastasis 1 (TIAM1) (AA 1392-1591) antibody
TIAM1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-T-Cell Lymphoma Invasion and Metastasis 1 (TIAM1) (AA 1478-1506), (C-Term) antibodyTIAM1 适用: 人 WB 宿主: 兔 Polyclonal RB41848 unconjugated
anti-T-Cell Lymphoma Invasion and Metastasis 1 (TIAM1) (C-Term) antibodyVerified TIAM1 适用: 人 ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-T-Cell Lymphoma Invasion and Metastasis 1 (TIAM1) (AA 52-224) antibodyTIAM1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-T-Cell Lymphoma Invasion and Metastasis 1 (TIAM1) (AA 1478-1506) antibodyTIAM1 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-T-Cell Lymphoma Invasion and Metastasis 1 (TIAM1) (C-Term) antibodyTIAM1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-T-Cell Lymphoma Invasion and Metastasis 1 (TIAM1) (AA 1261-1397) antibodyTIAM1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- The stated application concentrations are suggested starting points. Titration of the TIAM1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the TIAM1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- TIAM1 (T-Cell Lymphoma Invasion and Metastasis 1 (TIAM1))
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别名
- TIAM1
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背景
- TIAM1 is a protein that plays a crucial role in cell migration and invasion. In T cell lymphoma, increased expression of TIAM1 has been associated with enhanced invasive capabilities of cancer cells. TIAM1 promotes the formation of invasive structures called invadopodia, which facilitate cancer cell movement through tissues. Additionally, TIAM1 has been shown to activate signaling pathways that promote metastasis, making it a key player in the spread of T cell lymphoma. Studies have demonstrated that targeting TIAM1 can inhibit T cell lymphoma invasion. By disrupting the activity of TIAM1, researchers have been able to reduce the ability of cancer cells to invade surrounding tissues. This suggests that TIAM1 could be a potential therapeutic target for inhibiting T cell lymphoma invasion and slowing down disease progression. Metastasis is a major concern in T cell lymphoma, as cancer cells can spread to distant organs and tissues, leading to poor prognosis. TIAM1 has been implicated in promoting the metastatic spread of T cell lymphoma cells. By targeting TIAM1, researchers have observed a decrease in the ability of cancer cells to metastasize, highlighting the potential of TIAM1 as a therapeutic target for preventing T cell lymphoma metastasis.
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UniProt
- Q13009
抗原
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