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P4HB 抗体 (AA 146-363)

The 兔 多克隆 anti-P4HB antibody (ABIN7870732) specifically detects P4HB in WB, ELISA, IF, FACS 和 IHC (p). The antibody is reactive with 人, 小鼠, 大鼠 和 猴 samples.
产品编号 ABIN7870732
发货至: 中国
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Quick Overview for P4HB 抗体 (AA 146-363) (ABIN7870732)

抗原

See all P4HB 抗体
P4HB (Prolyl 4-Hydroxylase, beta Polypeptide (P4HB))

适用

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人, 小鼠, 大鼠, 猴

宿主

  • 147
  • 27
  • 2

克隆类型

  • 114
  • 62
多克隆

标记

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This P4HB antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 19
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    • 5
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    • 4
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    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    AA 146-363

    原理

    PDI Antibody / P4HB

    纯化方法

    Antigen affinity purified

    免疫原

    Recombinant human protein (amino acids A146-D363) was used as the immunogen for the PDI antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the PDI antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the PDI antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    P4HB (Prolyl 4-Hydroxylase, beta Polypeptide (P4HB))

    别名

    PDI

    背景

    Protein disulfide-isomerase, also known as the beta-subunit of prolyl 4-hydroxylase (P4HB), is an enzyme that in humans encoded by the P4HB gene. This gene encodes the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex.

    UniProt

    P07237

    途径

    Maintenance of Protein Location, Cell RedoxHomeostasis, Lipid Metabolism
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