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PATZ1 抗体 (AA 145-680)

The 兔 多克隆 anti-PATZ1 antibody (ABIN7870729) specifically detects PATZ1 in WB, ELISA, IF 和 FACS. The antibody is reactive with 人 samples.
产品编号 ABIN7870729
发货至: 中国
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Quick Overview for PATZ1 抗体 (AA 145-680) (ABIN7870729)

抗原

See all PATZ1 (ZNF278) 抗体
PATZ1 (ZNF278) (Zinc Finger Protein 278 (ZNF278))

适用

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宿主

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克隆类型

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多克隆

标记

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This PATZ1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)
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    AA 145-680

    原理

    PATZ1 Antibody / POZ-, AT hook-, and zinc finger-containing protein 1

    纯化方法

    Antigen affinity purified

    免疫原

    An E.coli-derived human recombinant protein (amino acids M145-Q680) was used as the immunogen for the PATZ1 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the PATZ1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the PATZ1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    PATZ1 (ZNF278) (Zinc Finger Protein 278 (ZNF278))

    别名

    PATZ1

    背景

    POZ-, AT hook-, and zinc finger-containing protein 1 is a protein that in humans is encoded by the PATZ1 gene. The protein encoded by this gene contains an A-T hook DNA binding motif which usually binds to other DNA binding structures to play an important role in chromatin modeling and transcription regulation. Its Poz domain is thought to function as a site for protein-protein interaction and is required for transcriptional repression, and the zinc-fingers comprise the DNA binding domain. Since the encoded protein has typical features of a transcription factor, it is postulated to be a repressor of gene expression. In small round cell sarcoma, this gene is fused to EWS by a small inversion of 22q, then the hybrid is thought to be translocated (t(1,22)(p36.1,q12). The rearrangement of chromosome 22 involves intron 8 of EWS and exon 1 of this gene creating a chimeric sequence containing the transactivation domain of EWS fused to zinc finger domain of this protein. This is a distinct example of an intra-chromosomal rearrangement of chromosome 22. Four alternatively spliced transcript variants are described for this gene.

    UniProt

    Q9HBE1
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