APCS 抗体 (AA 143-223)
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Quick Overview for APCS 抗体 (AA 143-223) (ABIN7870697)
抗原
See all APCS 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- AA 143-223
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原理
- Serum Amyloid P Antibody (azide and preservative free)
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纯化方法
- Protein G affinity chromatography
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免疫原
- A recombinant human partial protein (amino acids 143-223) was used as the immunogen for the Serum Amyloid P antibody.
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亚型
- IgG2b, kappa
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应用备注
- Optimal dilution of the Serum Amyloid P antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the Serum Amyloid P antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- APCS (Amyloid P Component, Serum (APCS))
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别名
- Serum Amyloid P
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背景
- Serum amyloid P (SAP) is a glycoprotein belonging to the pentraxin family of proteins, which has a characteristic pentameric organization and calciumdependent ligand binding. Secreted by liver epithelial cells, SAP is found in serum and urine. Although the function of SAP has not been clearly established, it has been shown to interact with DNA and histones and is thought to play a role in scavenging nuclear material released from damaged circulating cells. Also designated PTX2, SAP is a precursor of the protein amyloid P component (AP), which is universally associated with the amyloid deposits in all forms of amyloidoses, including Alzheimer s disease. SAP is a decamer of ten identical, noncovalently linked subunits, each of which may be post-translationally modified by glycosylation.
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UniProt
- P02743
抗原
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