LAIR1 抗体 (AA 142-287)
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Quick Overview for LAIR1 抗体 (AA 142-287) (ABIN7870687)
抗原
See all LAIR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 142-287
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原理
- LAIR1 Antibody / CD305
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纯化方法
- Antigen affinity purified
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免疫原
- An E.coli-derived human recombinant protein (amino acids Q142-H287) was used as the immunogen for the LAIR1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the LAIR1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the LAIR1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- LAIR1 (Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1))
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别名
- LAIR1
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背景
- Leukocyte-associated immunoglobulin-like receptor 1 is a protein that in humans is encoded by the LAIR1 gene. The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including natural killer cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1, and may induce cell death in myeloid leukemias. Alternative splicing results in multiple transcript variants.
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UniProt
- Q6GTX8
抗原
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