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ABCE1 抗体 (AA 141-599)

This 兔 多克隆 antibody specifically detects ABCE1 in WB 和 IHC (p). It exhibits reactivity toward 斑马鱼.
产品编号 ABIN7870676
发货至: 中国
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Quick Overview for ABCE1 抗体 (AA 141-599) (ABIN7870676)

抗原

ABCE1 (RLI1) (ABC Transporter E Family Member 1 (RLI1))

适用

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  • 1
斑马鱼

宿主

  • 1

克隆类型

  • 1
多克隆

标记

  • 1
This ABCE1 antibody is un-conjugated

应用范围

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  • 1
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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    AA 141-599

    原理

    Zebrafish ATP binding cassette E1 Antibody / Abce1

    纯化方法

    Antigen affinity chromatography

    免疫原

    An E.coli-derived zebrafish ABCE1 recombinant protein (amino acids Q141-D599) was used as the immunogen for the Zebrafish ATP binding cassette E1 antibody.

    亚型

    Ig Fraction
  • 应用备注

    Optimal dilution of the Zebrafish ATP binding cassette E1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the Zebrafish ATP binding cassette E1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    ABCE1 (RLI1) (ABC Transporter E Family Member 1 (RLI1))

    别名

    ATP binding cassette E1

    背景

    ATP binding cassette E1 (ABCE1, also RNase L inhibitor) is an ATPase found in humans involved in viral assembly. It is a member of the ATP-binding cassette (ABC) transporters superfamily and OABP subfamily. ABCE1 inhibits the action of ribonuclease L. Ribonuclease L normally binds to 2-5A (5'-phosphorylated 2',5'-linked oligoadenylates) and inhibits the interferon-regulated 2-5A/RNase L pathway, which is used by viruses. ABCE1 heterodimerize with ribonuclease L and prevents its interaction with 2-5A, antagonizing the anti-viral properties of ribonuclease L, and allow the virus to synthesize viral proteins. It has also been implicated to have an effect in tumorcell proliferation and antiapoptosis.

    UniProt

    Q6TNW3
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