SOX3 抗体 (AA 141-285)
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Quick Overview for SOX3 抗体 (AA 141-285) (ABIN7870673)
抗原
See all SOX3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 141-285
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原理
- Zebrafish Sox3 Antibody / SRY-box 3
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纯化方法
- Antigen affinity chromatography
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免疫原
- E. coli-derived zebrafish Sox3 recombinant protein (amino acids Q141-Q285) was used as the immunogen for the Zebrafish Sox3 antibody.
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亚型
- Ig Fraction
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应用备注
- Optimal dilution of the Zebrafish Sox3 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Zebrafish Sox3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- SOX3 (SRY (Sex Determining Region Y)-Box 3 (SOX3))
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别名
- Sox3
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背景
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SRY-box transcription factor 3 (Sox3) is a member of the SoxB1 subfamily of transcription factors, which are key regulators of early embryonic development and neural differentiation. In zebrafish (Danio rerio), Sox3 plays a critical role in the formation of the nervous system, maintenance of neural progenitor identity, and early ectodermal patterning.
Sox3 is maternally deposited and is expressed in the neuroectoderm during early development. It acts as a transcriptional activator that promotes neural fate by regulating genes involved in progenitor cell maintenance and inhibiting premature neuronal differentiation. Sox3 also contributes to the development of the pituitary gland, sensory placodes, and hypothalamic structures.
Due to its conservation across vertebrates, zebrafish Sox3 serves as a powerful model for studying neurogenesis, pluripotency, and transcriptional regulation during early embryonic development. It is also used to investigate mechanisms of cell fate decisions, stem cell biology, and congenital neurological disorders.
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UniProt
- Q6EJB7
抗原
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