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SOX3 抗体 (AA 141-285)

This 兔 多克隆 antibody specifically detects SOX3 in WB. It exhibits reactivity toward 斑马鱼.
产品编号 ABIN7870673
发货至: 中国
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Quick Overview for SOX3 抗体 (AA 141-285) (ABIN7870673)

抗原

See all SOX3 抗体
SOX3 (SRY (Sex Determining Region Y)-Box 3 (SOX3))

适用

  • 40
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  • 1
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斑马鱼

宿主

  • 39
  • 1
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克隆类型

  • 40
  • 1
多克隆

标记

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This SOX3 antibody is un-conjugated

应用范围

  • 29
  • 22
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Western Blotting (WB)
  • 抗原表位

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    AA 141-285

    原理

    Zebrafish Sox3 Antibody / SRY-box 3

    纯化方法

    Antigen affinity chromatography

    免疫原

    E. coli-derived zebrafish Sox3 recombinant protein (amino acids Q141-Q285) was used as the immunogen for the Zebrafish Sox3 antibody.

    亚型

    Ig Fraction
  • 应用备注

    Optimal dilution of the Zebrafish Sox3 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the Zebrafish Sox3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    SOX3 (SRY (Sex Determining Region Y)-Box 3 (SOX3))

    别名

    Sox3

    背景

    SRY-box transcription factor 3 (Sox3) is a member of the SoxB1 subfamily of transcription factors, which are key regulators of early embryonic development and neural differentiation. In zebrafish (Danio rerio), Sox3 plays a critical role in the formation of the nervous system, maintenance of neural progenitor identity, and early ectodermal patterning.

    Sox3 is maternally deposited and is expressed in the neuroectoderm during early development. It acts as a transcriptional activator that promotes neural fate by regulating genes involved in progenitor cell maintenance and inhibiting premature neuronal differentiation. Sox3 also contributes to the development of the pituitary gland, sensory placodes, and hypothalamic structures.

    Due to its conservation across vertebrates, zebrafish Sox3 serves as a powerful model for studying neurogenesis, pluripotency, and transcriptional regulation during early embryonic development. It is also used to investigate mechanisms of cell fate decisions, stem cell biology, and congenital neurological disorders.

    UniProt

    Q6EJB7
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