FDFT1 抗体 (AA 140-170)
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北京 101111
Quick Overview for FDFT1 抗体 (AA 140-170) (ABIN7870661)
抗原
See all FDFT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 140-170
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原理
- Squalene synthase Antibody / SQS / FDFT1
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纯化方法
- Purified
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免疫原
- A portion of amino acids 140-170 from the human protein was used as the immunogen for the Squalene synthase antibody.
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亚型
- Ig Fraction
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应用备注
- The stated application concentrations are suggested starting points. Titration of the Squalene synthase antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Squalene synthase antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- FDFT1 (Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1))
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别名
- Squalene synthase
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背景
- FDFT1 / Squalene synthase catalyzes the first step in the cholesterol biosynthetic pathway, the conversion of trans-farnesyldiphosphate to squalene. The loss of promoter activity and response to sterols for FDFT1 is localized to a 69-bp section positioned 131 bp 5-prime to the transcription start site. Sequence analysis of this region shows that it contains a sterol regulatory element-1 (SRE1) previously identified in other sterol regulated genes and 2 putative NF1 binding sites.
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UniProt
- P37268
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途径
- Regulation of Lipid Metabolism by PPARalpha
抗原
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