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FDFT1 抗体 (AA 140-170)

This 兔 多克隆 antibody specifically detects FDFT1 in WB 和 IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7870661
发货至: 中国
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北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for FDFT1 抗体 (AA 140-170) (ABIN7870661)

抗原

See all FDFT1 抗体
FDFT1 (Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1))

适用

  • 77
  • 39
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  • 2
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  • 2
  • 2
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  • 2
  • 1
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宿主

  • 78
  • 8

克隆类型

  • 65
  • 21
多克隆

标记

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This FDFT1 antibody is un-conjugated

应用范围

  • 71
  • 43
  • 32
  • 18
  • 18
  • 18
  • 5
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  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 9
    • 7
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    • 5
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    • 3
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    • 1
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    AA 140-170

    原理

    Squalene synthase Antibody / SQS / FDFT1

    纯化方法

    Purified

    免疫原

    A portion of amino acids 140-170 from the human protein was used as the immunogen for the Squalene synthase antibody.

    亚型

    Ig Fraction
  • 应用备注

    The stated application concentrations are suggested starting points. Titration of the Squalene synthase antibody may be required due to differences in protocols and secondary/substrate sensitivity.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the Squalene synthase antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    FDFT1 (Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1))

    别名

    Squalene synthase

    背景

    FDFT1 / Squalene synthase catalyzes the first step in the cholesterol biosynthetic pathway, the conversion of trans-farnesyldiphosphate to squalene. The loss of promoter activity and response to sterols for FDFT1 is localized to a 69-bp section positioned 131 bp 5-prime to the transcription start site. Sequence analysis of this region shows that it contains a sterol regulatory element-1 (SRE1) previously identified in other sterol regulated genes and 2 putative NF1 binding sites.

    UniProt

    P37268

    途径

    Regulation of Lipid Metabolism by PPARalpha
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